paraformaldehyde pubchem

Here in this study, to explore the potential application of antimicrobial peptide in wound healing, biodegradable poly(l-lactic acid)-Pluronic L35-poly(l-lactic acid) (PLLA-L35-PLLA) was developed at first. [6], Except where otherwise noted, data are given for materials in their, "Be Wary of Sargenti Root Canal Treatment | Quackwatch", "MSDS - 158127 SAFETY DATA SHEET - Paraformaldehyde", https://en.wikipedia.org/w/index.php?title=Paraformaldehyde&oldid=1077631025, Chemicals that do not have a ChemSpider ID assigned, Articles containing unverified chemical infoboxes, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 17 March 2022, at 10:23. Once paraformaldehyde is depolymerized, the resulting formaldehyde may be used as a fumigant, disinfectant, fungicide, and fixative. PDBe is the European resource for the collection, organisation and dissemination of data on biological macromolecular structures. In histology and pathology specimens preparation, usually, the fixation step is performed using 10% Neutral Buffered Formalin (4% formaldehyde) for, at least, 24 hours. Aggregated Computational Toxicology Online Resource (ACToR). Rhea is a freely available, manually annotated database of biochemical reactions. We use cookies to help provide and enhance our service and tailor content and ads. As a result, AP-57-NPs-H released AP-57 in an extended period and exhibited quite low cytotoxicity and high anti-oxidant activity in vitro. [Na+], CAS: 30525-89-4 Molecular Formula: CH2O Molecular Weight (g/mol): 30.026 MDL Number: MFCD00133991 InChI Key: WSFSSNUMVMOOMR-UHFFFAOYSA-N Synonym: formalin, formic aldehyde, formol, methanal, methyl aldehyde, methylene oxide, oxomethane, oxymethylene, paraform, paraformaldehyde PubChem CID: 712 ChEBI: CHEBI:16842 IUPAC Name: formaldehyde SMILES: C=O, CAS: 73-22-3 Molecular Formula: C11H12N2O2 Molecular Weight (g/mol): 204.229 MDL Number: MFCD00064340 InChI Key: QIVBCDIJIAJPQS-VIFPVBQESA-N Synonym: ardeytropin, h-trp-oh, l-tryptophan, l-tryptophane, optimax, s-tryptophan, trofan, tryptacin, tryptophan, tryptophane PubChem CID: 6305 ChEBI: CHEBI:16828 IUPAC Name: (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N, CAS: 9012-76-4 Molecular Formula: C56H103N9O39 Molecular Weight (g/mol): 1526.464 MDL Number: MFCD00161512 InChI Key: FLASNYPZGWUPSU-SICDJOISSA-N Synonym: chicol, chitosan, deacetylchitin, flonac c, flonac n, kimitsu chitosan f, kytex h, kytex m, poliglusam, sea cure plus PubChem CID: 71853 IUPAC Name: methyl N-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hy SMILES: COC(=O)NC1C(C(C(OC1OC2C(OC(C(C2O)N)OC3C(OC(C(C3O)N)O)CO)CO)CO)OC4C(C(C(C(O4)CO)OC5C(C(C(C(O5)CO)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)OC9C(C(C(C(O9)CO)O)O)N)O)N)O)N)O)N)O)N)O)N)O, CAS: 56-86-0 Molecular Formula: C5H9NO4 Molecular Weight (g/mol): 147.13 MDL Number: MFCD00002634 InChI Key: WHUUTDBJXJRKMK-UHFFFAOYNA-N Synonym: 2s-2-aminopentanedioic acid, glutacid, glutamic acid, glutamicol, glutamidex, glutaminol, h-glu-oh, l-glutamic acid, l-glutaminic acid, s-2-aminopentanedioic acid PubChem CID: 33032 ChEBI: CHEBI:16015 IUPAC Name: 2-aminopentanedioic acid SMILES: NC(CCC(O)=O)C(O)=O, CAS: 56-45-1 Molecular Formula: C3H7NO3 Molecular Weight (g/mol): 105.093 InChI Key: MTCFGRXMJLQNBG-REOHCLBHSA-N Synonym: 2s-2-amino-3-hydroxypropanoic acid, beta-hydroxyalanine, h-ser-oh, l---serine, l-ser, l-serine, s-2-amino-3-hydroxypropanoic acid, s-serine, serine, serine, l PubChem CID: 5951 ChEBI: CHEBI:17115 IUPAC Name: (2S)-2-amino-3-hydroxypropanoic acid SMILES: C(C(C(=O)O)N)O, CAS: 52-90-4 Molecular Formula: C3H7NO2S Molecular Weight (g/mol): 121.154 MDL Number: MFCD00064306 InChI Key: XUJNEKJLAYXESH-REOHCLBHSA-N Synonym: 2r-2-amino-3-sulfanylpropanoic acid, cystein, cysteine, half-cystine, l-+-cysteine, l-cystein, l-cysteine, r-2-amino-3-mercaptopropanoic acid, r-cysteine, thioserine PubChem CID: 5862 ChEBI: CHEBI:17561 IUPAC Name: (2R)-2-amino-3-sulfanylpropanoic acid SMILES: C(C(C(=O)O)N)S, CAS: 16373-93-6 Molecular Formula: C10H13N5O3 Molecular Weight (g/mol): 251.25 MDL Number: MFCD00149364 InChI Key: OLXZPDWKRNYJJZ-UHFFFAOYNA-N Synonym: 2'-deoxyadenosine hydrate, 2'-deoxyadenosine monohydrate, 2-deoxyadenosine hydrate, 2-deoxyadenosine monohydrate, 2?-deoxyadenosine monohydrate, 2r,3s,5r-5-6-amino-9h-purin-9-yl-2-hydroxymethyl tetrahydrofuran-3-ol hydrate, 9-2-deoxy-, a-d-ribofuranosyl adenine, adenosine, 2'-deoxy-, monohydrate, deoxyadenosine hydrate, deoxyadenosine monohydrate PubChem CID: 9549172 IUPAC Name: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate SMILES: NC1=C2N=CN(C3CC(O)C(CO)O3)C2=NC=N1, Electrophoresis, Western Blotting and ELISA, Chromatography and Mass Spectrometry Reagents, Histology, Cytology & Anatomical Pathology, Chlorine and pH Test Kits and Test Strips, Chemical Storage and Management Resource Center. AP-57-NPs were further encapsulated in a thermosensitive hydrogel (AP-57-NPs-H) to facilitate its application in cutaneous wound repair. [4], As a formaldehyde releasing agent, paraformaldehyde is a potential carcinogen. Copyright 2022 Elsevier B.V. or its licensors or contributors. ScienceDirect is a registered trademark of Elsevier B.V. ScienceDirect is a registered trademark of Elsevier B.V. Ketamine hydrochloride (PubChem CID: 15851). Paraformaldehyde can be depolymerized to formaldehyde gas by dry heating[2] and to formaldehyde solution by water in the presence of a base, an acid or heat. Paraformaldehyde is not a fixative; it must be depolymerized to formaldehyde in solution. endstream endobj 315 0 obj <. aesar alfa brands CompTox provides a high quality public chemistry resource for supporting improved predictive toxicology. Paraformaldehyde commonly has a slight odor of formaldehyde due to decomposition. [Na+], CAS: 51-05-8 Molecular Formula: C13H21ClN2O2 Molecular Weight (g/mol): 272.77 MDL Number: MFCD00013000 InChI Key: HCBIBCJNVBAKAB-UHFFFAOYSA-N Synonym: 2-diethylamino ethyl 4-aminobenzoate hydrochloride, aminocaine, anadolor, atoxicocaine, chlorocaine, geriocaine, gerovital h3, neotonocaine, procaine hcl, procaine hydrochloride PubChem CID: 5795 ChEBI: CHEBI:8431 IUPAC Name: 2-(diethylamino)ethyl 4-aminobenzoate;hydrochloride SMILES: [H+]. %PDF-1.6 % Moreover, AP-57-NPs-H was free-flowing liquid at room temperature, and can form non-flowing gel without any crosslink agent upon applied on the wounds. 352 0 obj <>/Filter/FlateDecode/ID[<1C6208C2DFBDC14DBE3341F4E62EC924><424FD6349744014B9E21753367C6D730>]/Index[314 58]/Info 313 0 R/Length 158/Prev 297636/Root 315 0 R/Size 372/Type/XRef/W[1 3 1]>>stream Odor and/or flavor descriptions from others (if found).

The resulting formaldehyde gas from dry heating paraformaldehyde is flammable. 0 Download : Download high-res image (211KB)Download : Download full-size image. hbbd```b``+@$d5l3jl[0{m&fHY$SAlS]`M21n2``L>Sj"A^0 w% s& H,9{ Please sign in to view account pricing and product availability. ArrayExpress is a public repository for transcriptomics and related data. indirect food additives: adhesives and components of coatings, Predict (works with chrome, Edge or firefox), Atomic Weights of the Elements 2011 (pdf). %%EOF System for the Analysis of Biochemical Pathways - Reaction Kinetics. A curated knowledgebase of biological pathways. A database of measured binding affinities, focusing on the interactions of proteins considered to be drug-targets with small, drug-like molecules. A knowledge resource for lipids and their biology.

Paraformaldehyde can be used as a substitute of aqueous formaldehyde to produce the resinous binding material, which is commonly used together with melamine, phenol or other reactive agents in the manufacturing of particle board, medium density fiberboard and plywood. NMRShiftDB is a NMR database for organic structures and their nuclear magnetic resonance (nmr) spectra. Once paraformaldehyde is depolymerized, the resulting formaldehyde may be used as a fumigant, disinfectant, fungicide, and fixative. [Cl-].CCN(CC)CCOC(=O)C1=CC=C(N)C=C1, CAS: 68855-54-9 Molecular Formula: CNa2O3 Molecular Weight (g/mol): 105.988 MDL Number: MFCD00132803 InChI Key: CDBYLPFSWZWCQE-UHFFFAOYSA-L Synonym: Diatomaceous Earth, Kieselguhr PubChem CID: 10340 ChEBI: CHEBI:29377 IUPAC Name: disodium;carbonate SMILES: C(=O)([O-])[O-].[Na+]. MetaboLights is a database for Metabolomics experiments and derived information. PubChem is a database of molecules and their properties. SID numbers link to information submitted to PubChem by ChEBI; CID numbers link to a summary of information from all submitters. UniProt Knowledge Base of protein sequences. nitropyridine methyl oxide Accumulating evidence shows that antimicrobial peptides play pivotal roles in the process of wound healing. In situ gel-forming system as local drug delivery system in dermal traumas has generated a great interest. formaldehyde aldrich solution 13c Then based on this polymer, an injectable in situ gel-forming system composed of human antimicrobial peptides 57 (AP-57) loaded nanoparticles and thermosensitive hydrogel was prepared and applied for cutaneous wound healing. BRENDA Ligands refer to all compounds which interact with enzymes. In vivo wound healing assay using full-thickness dermal defect model of SD rats indicated that AP-57-NPs-H could significantly promote wound healing.

https://doi.org/10.1016/j.ijpharm.2015.09.005. Paraformaldehyde is also used to crosslink proteins to DNA, as used in ChIP (chromatin immunoprecipitation) which is a technique to determine which part of DNA certain proteins are binding to. Paraformaldehyde forms slowly in aqueous formaldehyde solutions as a white precipitate, especially if stored in the cold. Histopathological examination suggested that AP-57-NPs-H could promote cutaneous wound healing through enhancing granulation tissue formation, increasing collagen deposition and promoting angiogenesis in the wound tissue.

Therefore, AP-57-NPs-H might have potential application in wound healing. Copyright 2015 Elsevier B.V. All rights reserved. A Database of information on naturally occurring carotenoids from many organisms extracted from the literature. 371 0 obj <>stream Longer chain-length (high molecular weight) polyoxymethylenes are used as a thermoplastic and are known as polyoxymethylene plastic (POM, Delrin). Recommendation for para-formaldehyde usage levels up to: Recommendation for para-formaldehyde flavor usage levels up to: NIOSH International Chemical Safety Cards: National Institute of Allergy and Infectious Diseases: FDA Indirect Additives used in Food Contact Substances. Paraformaldehyde is a poly-acetal. These authors contributed equally to this work. Formalin actually contains very little monomeric formaldehyde; most of it forms short chains of polyformaldehyde. Biology-related abstracts of patent applications. NURSA (Nuclear Receptor Signaling Atlas) is an online information resource for the nuclear receptor signaling community. US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Use: Paraformaldehyde can be depolymerized to formaldehyde gas by dry heating and to form a formaldehyde solution by water in the presence of a base or heat.

Paraformaldehyde (PFA) is the smallest polyoxymethylene, the polymerization product of formaldehyde with a typical degree of polymerization of 8100 units. A database of mass spectra from metabolites quantified using gas chromatography (GC) coupled to mass spectroscopy (MS). The Gene Ontology (GO) knowledgebase is the worlds largest source of information on the functions of genes. [5] Its acute oral median lethal dose in rats is 592mg/kg. 314 0 obj <> endobj AP-57 peptides were enclosed with biocompatible nanoparticles (AP-57-NPs) with high drug loading and encapsulation efficiency. Classification of the substance or mixture, GHS Classification in accordance with 29 CFR 1910 (OSHA HCS), GHS Label elements, including precautionary statements. X2if=p'0tb 0 * CAS: 64-18-6 Molecular Formula: CH2O2 Molecular Weight (g/mol): 46.025 MDL Number: MFCD00003297 InChI Key: BDAGIHXWWSANSR-UHFFFAOYSA-N Synonym: acide formique, aminic acid, bilorin, collo-bueglatt, formira, formisoton, formylic acid, hydrogen carboxylic acid, methanoic acid, myrmicyl PubChem CID: 284 ChEBI: CHEBI:30751 IUPAC Name: formic acid SMILES: C(=O)O, CAS: 30525-89-4 Molecular Formula: CH2O Molecular Weight (g/mol): 30.03 MDL Number: MFCD00003274,MFCD00133991 InChI Key: WSFSSNUMVMOOMR-UHFFFAOYSA-N Synonym: formalin, formic aldehyde, formol, methanal, methyl aldehyde, methylene oxide, oxomethane, oxymethylene, paraform, paraformaldehyde PubChem CID: 712 ChEBI: CHEBI:16842 IUPAC Name: formaldehyde SMILES: C=O, CAS: 7048-04-6 Molecular Formula: C3H10ClNO3S Molecular Weight (g/mol): 175.63 InChI Key: QIJRTFXNRTXDIP-JIZZDEOASA-N Synonym: cysteine hcl, cysteine hydrochloride monohydrate, l, h-cys-oh.hcl.h2o, h-cys-ohhclh2o, l-cysteine hydrate hydrochloride, l-cysteine hydrochloride hydrate, l-cysteine hydrochloride monohydrate, l-cysteine monohydrate monochloride, r-2-amino-3-mercaptopropanoic acid hydrochloride hydrate, unii-zt934n0x4w PubChem CID: 23462 IUPAC Name: (2R)-2-amino-3-sulfanylpropanoic acid;hydrate;hydrochloride SMILES: C(C(C(=O)O)N)S.O.Cl, CAS: 68855-54-9 Molecular Formula: CNa2O3 Molecular Weight (g/mol): 105.988 MDL Number: MFCD00146688 InChI Key: CDBYLPFSWZWCQE-UHFFFAOYSA-L PubChem CID: 10340 ChEBI: CHEBI:29377 IUPAC Name: disodium;carbonate SMILES: C(=O)([O-])[O-].[Na+]. A database of evidence for molecular interactions, A database of bioactive drug-like small molecules and associated bioactivities abstracted from the scientific literature. A biochemical knowledge-base on human metabolism. hb```l@9:Ar{cGG+C*P` !1'K2[ d*6\]FF+_n2aL`Tcfc4,|\,Y SureChEMBL provides free access to chemical data extracted from the patent literature. In cell culture, a typical formaldehyde fixing procedure would involve using a 4% formaldehyde solution in phosphate buffered saline (PBS) on ice for 10 minutes. The high purity formaldehyde solutions obtained in this way are used as a fixative for microscopy and histology. Database of Mathematical models of biological interest. CAS: 56-40-6 Molecular Formula: C2H5NO2 Molecular Weight (g/mol): 75.07 MDL Number: MFCD00008131 InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N Synonym: aciport, aminoacetic acid, aminoethanoic acid, glicoamin, glycine, glycocoll, glycolixir, glycosthene, hampshire glycine, padil PubChem CID: 750 ChEBI: CHEBI:15428 IUPAC Name: 2-aminoacetic acid SMILES: NCC(O)=O, CAS: 50-00-0 Molecular Formula: CH2O Molecular Weight (g/mol): 30.03 MDL Number: MFCD00003274,MFCD00133991 InChI Key: WSFSSNUMVMOOMR-UHFFFAOYSA-N Synonym: formalin, formic aldehyde, formol, methanal, methyl aldehyde, methylene oxide, oxomethane, oxymethylene, paraform, paraformaldehyde PubChem CID: 712 ChEBI: CHEBI:16842 IUPAC Name: formaldehyde SMILES: C=O, CAS: 50-00-0 Molecular Formula: CH4O Molecular Weight (g/mol): 32.04 MDL Number: MFCD00004595 InChI Key: OKKJLVBELUTLKV-UHFFFAOYSA-N IUPAC Name: methanol SMILES: CO. Vials of high-quality, methanol-free formaldehyde, a general IHC fixative and reversible amine-crosslinking agent for protein and nucleic acid samples. ArrayExpress (Repository of Microarray data). BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. At day 14 after operation, AP-57-NPs-H treated group showed nearly complete wound closure of 96.783.12%, whereas NS, NPs-H and AP-57-NPs group recovered by about 68.784.93%, 81.963.26% and 87.804.62%, respectively. [Na+], CAS: 64-18-6 Molecular Formula: CH2O2 Molecular Weight (g/mol): 46.025 InChI Key: BDAGIHXWWSANSR-UHFFFAOYSA-N Synonym: acide formique, aminic acid, bilorin, collo-bueglatt, formira, formisoton, formylic acid, hydrogen carboxylic acid, methanoic acid, myrmicyl PubChem CID: 284 ChEBI: CHEBI:30751 IUPAC Name: formic acid SMILES: C(=O)O, CAS: 9005-38-3 Molecular Formula: (C6H7O7)A(C6H7O7)BNa MDL Number: MFCD00081310 Synonym: Algin, Sodium alginate, CAS: 52450-18-7 Molecular Formula: C10H15N3O4 Molecular Weight (g/mol): 241.247 MDL Number: MFCD00038057 InChI Key: ADVCGXWUUOVPPB-XLPZGREQSA-N Synonym: 1-2r,4s,5s-4-amino-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione, 1-2r,4s,5s-4-amino-5-hydroxymethyl oxolan-2-yl-5-methylpyrimidine-2,4-dione, 1-2r,4s,5s-4-amino-5-hydroxymethyl tetrahydrofuran-2-yl-5-methyl-pyrimidine-2,4-dione, 1-2r,4s,5s-4-amino-5-hydroxymethyl tetrahydrofuran-2-yl-5-methylpyrimidine-2,4 1h,3h-dione, 3'-amino-2',3'-dideoxythymidine, 3'-amino-3'-deoxy-d-thymidine, 3'-amino-3'-deoxythymidine, 3'-deoxy-3'-aminothymidine, thymidine, 3'-amino-3'-deoxy, unii-7w21m0c25b PubChem CID: 108074 IUPAC Name: 1-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione SMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N, CAS: 609-99-4 Molecular Formula: C7H4N2O7 Molecular Weight (g/mol): 228.12 MDL Number: MFCD00007104 InChI Key: LWFUFLREGJMOIZ-UHFFFAOYSA-N Synonym: 2-hydroxy-3,5-dinitrobenzoic acid, 3,5-dinitro-2-hydroxybenzoic acid, 3,5-dinitro-2-salicylic acid, 3,5-dinitrosalicylate, 3,5-dinitrosalicylic acid, benzoic acid, 2-hydroxy-3,5-dinitro, dnsa, o-dinitrocarboxylphenol, o-dncp, salicylic acid, 3,5-dinitro PubChem CID: 11873 ChEBI: CHEBI:53648 SMILES: C1=C(C=C(C(=C1[N+](=O)[O-])O)C(=O)O)[N+](=O)[O-], CAS: 56-85-9 Molecular Formula: C5H10N2O3 Molecular Weight (g/mol): 146.15 MDL Number: MFCD00008044 InChI Key: ZDXPYRJPNDTMRX-VKHMYHEASA-N Synonym: cebrogen, glumin, glutamic acid amide, glutamine, h-gln-oh, l-+-glutamine, l-glutamine, levoglutamid, levoglutamide, stimulina PubChem CID: 5961 ChEBI: CHEBI:18050 IUPAC Name: (2S)-2,5-diamino-5-oxopentanoic acid SMILES: N[C@@H](CCC(N)=O)C(O)=O, CAS: 79-09-4 Molecular Formula: C3H6O2 Molecular Weight (g/mol): 74.079 InChI Key: XBDQKXXYIPTUBI-UHFFFAOYSA-N Synonym: carboxyethane, ethanecarboxylic acid, ethylformic acid, luprosil, metacetonic acid, methylacetic acid, monoprop, propionic acid, prozoin, pseudoacetic acid PubChem CID: 1032 ChEBI: CHEBI:30768 IUPAC Name: propanoic acid SMILES: CCC(=O)O, CAS: 68855-54-9 Molecular Formula: CNa2O3 Molecular Weight (g/mol): 105.988 InChI Key: CDBYLPFSWZWCQE-UHFFFAOYSA-L Synonym: Calcinated diatomaceous earth, Diatomite PubChem CID: 10340 ChEBI: CHEBI:29377 IUPAC Name: disodium;carbonate SMILES: C(=O)([O-])[O-].[Na+]. A small amount of methanol is often added as a stabilizer to limit the extent of polymerization. By continuing you agree to the use of cookies. endstream endobj startxref It was used in the past in the discredited Sargenti method of root canal treatment.[3].