Method: The study included all neonates with congenital anomalies referred to Asir Central Hospital from 1997 to 2002. (1) Maternal pregestational diabetes mellitus is associated with an increased risk for congenital malformations of about2-4 times the background risk. abortions. Neural tube defect (NTD) was found to be the commonest (65.8%) type of anomaly. The distribution pattern of anomalies according to the system involved showed that 41.7% was Central Nervous System anomaly, 8.7% was Renal anomaly, 6.5% was Musculoskeletal anomaly, 4.4% was Gastrointestinal anomaly,6.6% had body wall defect, 10.9 % was Nonimmune Hydrops, 3.3% was Syndromic baby and 13.1% had multiple congenital The pattern and preva-lence of congenital anomalies may vary over time or with geographical location. What are the 4 categories of birth defects?Cleft lip or cleft palate.Heart defects, such as missing or misshaped valves.Abnormal limbs, such as a clubfoot.Neural tube defects, such as spina bifida, and problems related to the growth and development of the brain and spinal cord. Congenital malformations are rapidly emerging as one of the major worldwide problems. Genetic disorders constituted 18.6% of all types of CAs in 2010. Congenital anomalies are important causes of childhood death, chronic illness and disability in many countries. Thirdly, even when researchers establish an association between an environmental exposure and birth outcome, establishing causation and interaction with other confounding exposures is challenging. congenital anomalies is still a significant problem in our area. Congenital anomalies of the kidneys and urinary tract (CAKUT) comprise various entities of structural malformations that result from defects in morphogenesis of the kidney and/or urinary tract. Thus, there were a total of 74 anomalies among 63 newborn babies. Little is known about the prevalence and pattern of congenital anomalies in Central Vietnam. A high prevalence of congenital anomalies in one year among live born neonates delivered in Zagazig University Hospital revealed and the importance of carrying out a thorough clinical examination of all neonates at birth was stressed. 8. We conducted a prospective population-basedstudy in Kuwait to determine the prevalence andpattern of previously undiagnosed congenitalanomalies of urinary tract in patientsundergoing intravenous urography (IVU) and toexamine the demographic factors associated withthese anomalies. Major anomalies occur in about 2.5%4.0% of live births but minor defects are more common in the population. Birth defects are divided into two main types: structural disorders in which problems are seen with the shape of Congenital anomalies were considered in the context of the presumed pathogenetic mechanism related to the neurotropic properties of the virus. The incidence of birth defects was 2.6%, and the 2 most common anomalies were congenital heart disease and muscular-skeletal system anomalies, significantly associated with male gender, prematurity and low birth weight. The current study is unique in the sense that it has a large sample size; it presents pattern of congenital anomalies among infertile women that were seen in a private fertility center in Lagos, Nigeria and it covers an extensive period of time - 2003 to 2014. 
Examples include: maternal nutritional status; exposure to chemicals, and possibly illicit drugs; maternal infections (e.g. "Pattern of Congenital Anomalies in Newborn: A Hospital-Based Study" Pediatric Reports 5, no. Methods. Objectives: To evaluate the prevalence and pattern of congenital coronary artery anomalies (CAAs) in the adult population undergoing catheter coronary angiography. Results: The study revealed that congenital anomalies of the digestive system (38.0%), musculoskeletal system (32.9%), and circulatory system (11.0%) were the most common types of CAs. The pattern and preva-lence of congenital anomalies may vary over time or with geographical location. The congenital anomalies were seen more (4.93%) in neonates born to young mothers (= 20 years) and again there was an increase Out of these, 56 had a sin-gle congenital anomaly and the other 18 (28.6%) had multiple malformations. Thus, there were a total of 74 anomalies among 63 newborn babies. Introduction. JCPSP 2007, 17: 340-43. 84.7% patients were males and 15.3% were females which could be because of The patterns of congenital anomalies may differ over time or by geographical location, which may reflect complex interactions between environmental and genetic issues . West Afr J Med. Surveillance, used to identify all malformed infants in a consecutive sample of births, can identify a distinctive pattern of malformations among the affected infants. The pattern of congenital anomalies related to head and neck, chest and gastrointestinal tract (20.75%), nervous system (19. doi: 10.4081/pr.2013.e5. The patterns of congenital anomalies may be different between regions and the actual numbers may vary significantly between countries . of incidence of congenital anomalies in a popu-lation. This was Few population-based studies have analyzed patterns of co-occurring birth defects among those with trisomy 13. Few population-based studies have analyzed patterns of co-occurring birth defects among those with trisomy 13. The most common, severe congenital anomalies are heart defects, neural tube defects and Down syndrome. Although congenital anomalies may be the result of one or more genetic, infectious, nutritional or environmental factors, it is often difficult to identify the exact causes. Some congenital anomalies can be prevented. Objective: The study was to know the common congenital anomalies and their outcome in a tertiary referral centre. A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Methods A retrospective descriptive study was done. 
Recognising into which group a patients anomalies fall can inform genetic risks, prognosis and appropriate management. Evaluating the patterns of MCAs can provide clues to the underlying causes, pathogenic mechanisms, and developmental pathways. J Coll Physicians Surg Pak 2007;17:340-3. Globally, an estimated 303,000 newborns die within 4 weeks of birth every year from congenital anomalies. Congenital anomalies are a major cause of stillbirths and neonatal mortality. Most anomalies have multifactorial causes and commonly affect the central nervous, cardiovascular, gastrointestinal and musculoskeletal systems. How to determine the causes and recurrence risks of congenital anomalies - a clinical approach. Ultrasound findings include The most frequent associated risk factor was history of consanguineous marriage in 44.74%. Gillani S, Kazmi NH, Najeeb S, Hussain S, Raza A. Frequencies of congenital anomalies among newborns admitted in nursery of Ayub Teaching Hospital Abbottabad, Pakistan. This study was aimed at identifying the patterns of congenital anomalies treated by surgeons from HEAL Africa Teaching Hospital over the last thirteen years and determining the significant barriers to earlier care. A baby may have a single anomaly or a complex pattern of anomalies affecting many different body systems. Parveen F, Tayyub S. Frequency and pattern of congenital anomalies in the newborn and associated maternal risk factors. Analysis of trends in congenital anomaly-attributed infant mortality, using the 19811995 Statistics Canada's birth and death records, with a total of 2,878,826 live births, 21,883 infant deaths, and 6,908 infant deaths due to congenital Congenital obstruction of the UPJ is a common anomaly of the urinary tract. Table 2 shows that among infants with CAs, 70.6% were males and 29.4% were females. Results: Out of 859 admissions 59 were diagnosed to be suffering from congenital anomalies. In craniospinal system most common congenital anomaly is Anencephaly (26%). Professor P A Farndon. However, the problem related to congenital anomalies especially the NTDs have not been declined in the needed manner in developing nations including Ethiopia [11,15, 31, 32]. Conclusions: Major maternal risk factor identified among the study group was history of previous. Background. Congenital malformations are rapidly emerging as one of the major worldwide problems. The aim of this pa-per is to determine the pattern of congenital anomalies in newborns and to study maternal and peri-natal risk factors. Congenital anomalies of the kidneys and urinary tract (CAKUT) comprise various entities of structural malformations that result from defects in morphogenesis of the kidney and/or urinary tract. Background. In studies from Iran musculoskeletal anomalies rank as the The patterns of congenital anomalies may differ over time or by geographical location, which may reflect complex interactions between environmental and genetic issues . Out of 2517 newborns, 63 had one or other congenital anomaly accounting for an incidence of 2.5%.
Hypoplastic left heart syndromeCommon truncusInterrupted aortic archTransposition of great arteriesTetralogy of FallotPulmonary valve atresiaTricuspid valve atresia Results: The incidence of congenital anomalies in this study was 2.48% of the total number of fetus and babies born after 12 weeks of gestation in our hospital during a period of two year. The true epidemiology of congenital anomalies in northern Tanzania is still obscure. Participants Saudi women enrolled during pregnancy over 3 years and their 28 646 eligible pregnancy outcomes (births, Keywords . About 94% of severe congenital anomalies occur in low- and middle-income countries. Background Congenital anomalies are major causes of morbidity and mortality in children under 5 years of age and make a significant contribution to the surgical burden of diseases. Fifty-five percent of congenital spine deformity patients (n = 41) had associated spinal cord anomalies on MRI.Complex bony abnormalities had a higher incidence of cord anomalies than simple abnormalities (67, 37 %; p = 0.011). Mixed deformities of segmentation and formation had a higher incidence of cord anomalies (73 %) than failures of formation (50 %) or segmentation 1.4 Congenital Anomalies - Definitions. How to determine the causes and recurrence risks of congenital anomalies - a clinical approach. Abstract There is overwhelming evidence that vitamin A (retinol), presumably through its metabolite retinoic acid, participates in organogenesis Sequence Multiple congenital anomaly is the occurrence of two or more major anomalies that are __________ The incidence of birth defects was 2.6%, and the 2 most common anomalies were congenital heart disease and muscular-skeletal system anomalies, significantly associated with male gender, prematurity and low birth weight. The pattern of congenital anomalies is shown in table-1.
